Declotting Picc Line With Activase
This substance dissolves fibrin a substance that causes blood to clot breaking down the thrombus and restoring function.
Declotting picc line with activase. Repeat x1 for 2 hours if not successful. This is done by a nurse using activase injected directly into the line. Attach the 3 ml syringe with the activase to the catheter unclamp catheter. Draw back on the empty syringe creating a vacuum in the picc line between the stop cock and the clot switch the stop cock to the cathflo and the tpa is sucked up to the clot.
Children and adolescents weighing 30 kg or more instill 2 mg 2 ml into the dysfunctional catheter for 2 hours. Reapply old injection cap. The patient is taken to the treatment room for whatever time is required for the procedure and charged accordingly. As with all catheterization procedures care should be used to maintain aseptic technique.
Use of alteplase for declotting of catheters should trigger heightened awareness of infection risk. Repeat to other catheter port as needed. Apply label to affected port declotting catheter do not use with time date and initials. Thrombi in around a central line facilitate adhesion of bacteria.
Using cathflo activase in patients with infected catheters may release a localized infection into the systemic circulation. Cathflo activase alteplase is a tissue plasminogen activator t pa produced by recombinant dna technology. A clotted picc line can be relieved by injecting cathoflo activase or alteplase recombinant 1 mg hcpcs code j2997 directly into the line. How to declot a picc line using alteplase rtpa it can be very frustrating when you go to draw blood from a picc line and it is clotted off.
Let sit for 30 minutes draw the clot back into the syringe. Picc non tunneled tunneled implanted port includes volume of reservoir catheter and needle infusion set. Make sure to perform this using whatever policy is in place at your hospital. It is synthesized using the complementary dna cdna for natural human tissue type plasminogen activator t pa obtained from an established human cell line.
Lines suitable for declotting. Doses of 1 to 2 mg injected into the lumen s of central venous catheters or picc lines allowed to dwell for 15 minutes to 4 hours then removed by aspiration have been reported effective in establishing patency.